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Considerations for treatment sequencing in B-ALL

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Published: 23.01.20
Views: 615

Prof Nicola Gökbuget - Universitätsklinikum Frankfurt, Frankfurt, Germany

Prof Nicola Gökbuget speaks to ecancer at the 2020 ALL Assembly meeting in Frankfurt about the considerations for treatment sequencing in patients with B-cell acute lymphoblastic leukaemia (B-ALL) when treated with immunotherapy.

She describes the various immunotherapeutic options that are available for this disease type, including blinatumomab and inotuzumab - which both lead to better response rates compared to standard chemotherapy and should be the treatment of choice for early relapse/refractory patients.

However, Prof Gökbuget states that for patients who relapse later, there is currently a lack of data for both agents.

She discusses the challenge of choosing between blinatumomab and inotuzumab and which patient populations will benefit the most.


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