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Abstract | Full HTML Article | PDF ecancer 14 1010 / https://doi.org/10.3332/ecancer.2020.1010

Case Report

Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin

Most cutaneous adverse drug reactions reported in association with chemotherapy, such as a limited maculopapular rash, are considered mild and do not affect the continuation of the treatment. Toxic epidermal necrolysis (TEN), however, is a life-threatening reaction that needs treatment discontinuation. The present case shows the slow progression from a pemetrexed and carboplatin-associated maculopapular rash to a TEN-like reaction.

Keywords: toxic epidermal necrolysis, cutaneous adverse drug reactions, drug rash, pemetrexed

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European Cancer Organisation European Institute of Oncology

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ecancer Global Foundation