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ESMO 2019 /
Safety and tolerability of AVB500 in platinum-resistant recurrent ovarian cancer

27th Sep - 1st Oct 2019

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Published: 04.10.19
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Dr Gail McIntyre - CSO, Aravive Biologics, Houston, Texas

Dr Gail McIntyre speaks to ecancer at ESMO 2019 in Barcelona about a phase Ib study using AVB500 in combination with paclitaxel or pegylated liposomal doxorubicin in platinum-resistant recurrent ovarian cancer.

She explains they have identified a biomarker that allows them to understand what dose of AVB500 will give the desired pharmacodynamic response.

Dr McIntyre reports that AVB500 was found to be safe and tolerable in the small cohort of patients, and adds that the next steps are to increase doses to reach a level they have identified as being associated with response.

 

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· ESMO 2019

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Founding partners

European Cancer Organisation European Institute of Oncology

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Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

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ecancer Global Foundation