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2018 ASCO Annual Meeting /
Nelarabine in newly diagnosed paediatric T-cell malignancies

1st - 5th Jun 2018

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Published: 02.06.18
Views: 993

Dr Kimberly Dunsmore - University of Virginia School of Medicine, Virginia, USA

Dr Dunsmore speaks with ecancer at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting about the use of nelarabine in new cases of paediatric T cell malignancies.

She describes the structure of the COG AALL0434 trial, with almost 2,000 patients randomised to receive escalating dose methotrexate without leucovorin rescue pegaspargase (CMTX) or High Dose MTX (HDMTX) leucovorin rescue, and intermediate and high-risk patients with T-ALL and T-LL were randomised to receive six 5-day courses of nelarabine.

Nelarabine was found to improve DFS for children and young adults with T-ALL, leading Dr Dunsmore to encourage its use as a new standard of care for this population

ecancer's filming has been kindly supported by Amgen through the ECMS Foundation. ecancer is editorially independent and there is no influence over content.


Previous conferences: highlights

Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation